Regorafenib from MyBioSource.com

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Regorafenib

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Description

A multi-kinase inhibitor related to sorafenib1. Inhibits c-Raf, B-Raf, VEGFR1, VEGFR2, VEGFR3, Tie2, PDGFRbeta; FGFR1, c-Kit, and RET with IC50s=2.5, 28, 13, 4.2, 46, 311, 22, 202, 7 and 1.5 nM respectively1-2